Fig. 7.

TAF1 expression in nuclei in the striatum. TAF1 expression (red) is shown for 3- to 5-month-old female mice for the wild type (Wt) condition and the genotypes 2loxP heterozygous (het), 2loxP homozygous (hom) and 1loxP het (following cre recombination, bred with EIIa-Cre mice). The anti-CTIP2 antibody (green) was used to co-stain medium spiny neuron nuclei and DAPI (blue) was used to stain all nuclei. Images are representative of n=3 mice per genetic group. The experiment was replicated three times or more during the optimisation stage. Quantification of nuclei stained for CTIP2 and TAF1 is shown in Fig. S4A,B. Scale bars: 10 μm.