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. Author manuscript; available in PMC: 2024 Jul 22.
Published in final edited form as: Br J Sports Med. 2022 Sep 27;56(22):1277–1283. doi: 10.1136/bjsports-2021-105315

Table 2. Muscle strengthening and aerobic exercise associated with all-cause and cause-specific mortality with and without mutual adjustment.

(HR and 95% CIs). Weighted estimates to the whole cohort are presented.

All-cause mortality HR (95%CI) CVD mortality HR (95%CI) Cancer mortality HR (95%CI)

Deaths (n) Model A Model A + MVPA1 Model A Model A + MVPA Model A Model A + MVPA
Weightlifting
 Yes (vs. no)
3,835 0.79 (0.76–0.81) 0.91 (0.88–0.94) 0.76 (0.76–0.80) 0.91 (0.86–0.97) 0.85 (0.80–0.91) 0.96 (0.90–1.02)

Weightlifting frequency

Never 22,086 1.00 (ref) 1.00 (ref) 1.00 (ref) 1.00 (ref) 1.00 (ref) 1.00 (ref)

Less than once/month 300 0.82 (0.74–0.92) 0.84 (0.76–0.94) 0.84 (0.70–1.03) 0.86 (0.71–1.05) 0.88 (0.72–1.07) 0.91 (0.75–1.11)

One to three times/month 874 0.80 (0.75–0.85) 0.85 (0.79–0.91) 0.82 (0.73–0.92) 0.89 (0.79–0.99) 0.80 (0.71–0.90) 0.85 (0.75–0.96)

One to two times/week 1,712 0.76 (0.73–0.80) 0.86 (0.82–0.91) 0.73 (0.97–0.79) 0.85 (0.78–0.93) 0.88 (0.81–0.96) 0.97 (0.89–1.06)

Three to 7+ times/week 2,123 0.79 (0.75–0.82) 0.93 (0.89–0.98) 0.76 (0.71–0.82) 0.95 (0.88–1.03) 0.81 (0.75–0.88) 0.93 (0.85–1.01)


Per unit increase in weightlifting category 0.93 (0.92–0.94) 0.97 (0.96–0.98) 0.92 (0.91–0.94) 0.97 (0.96–0.99) 0.95 (0.93–0.96) 0.98 (0.96–0.99)

P for trend <.0001 <.0001 <.0001 0.002 <.0001 0.03

MVPA groups
None 11,203 1.00 (ref) 1.00 (ref) 1.00 (ref)
Some 9,574 0.76 (0.74–0.78) 0.73 (0.69–0.77) 0.78 (0.74–0.82)
Meets 5,365 0.68 (0.65–0.70) 0.65 (0.62–0.69) 0.70 (0.66–0.75)
Exceeds 1,788 0.66 (0.63–0.70) 0.65 (0.60–0.71) 0.70 (0.64–0.77)

Model A adjusted for age at follow-up questionnaire, sex, education, smoking, alcohol intake, current BMI category, race, and number of comorbidities.

1

MVPA abbreviates moderate to vigorous physical activity, these results include covariates from Model A plus each group of aerobic activity guidelines (inactive 0 minutes of activity, insufficient of 1–149 minutes of activity, meets guidelines 150–300 minutes of activity, highly active of 301+ minutes of activity).