Figure 2.

Mitophagy biomarkers vs Alzheimer disease (AD) phenotype. *, ** and *** denote p < 0.05, p < 0.01 and p < 0.001, respectively. Partial Pearson correlation for AD biomarkers, ATN and brain structures was adjusted for age and sex or in the case of cognition, for age, sex, and education. Blue asterisks denote significance after Holm-Bonferroni correction for multiple comparisons. CSF, cerebrospinal fluid; “A”, amyloid; “T”, tau; “N”, neurodegeneration; +, abnormal; -, normal; Aβ42/42, amyloid beta 42 to 40 ratio; Aβ42, amyloid beta 42; p-MAPT/tau (181), phosphorylated MAPT/tau (181); t-MAPT/tau, total MAPT/tau; NEFL, neurofilament light chain; NRGN, neurogranin.