Table 1. General characteristics of the study groups.
Variablesa | Controls (n=158) | Cases with nonalcoholic fatty liver disease (n=154) | p-value | |
---|---|---|---|---|
Age (years) | 28.9 (7.7) | 39.1 (9.1) | <0.001 | |
BMI (kg/m2) | 23.3 (3.5) | 29.5 (5.2) | <0.001 | |
Sex | ||||
Male | 83 (52.5) | 114 (74.0) | ||
Female | 75 (47.5) | 40 (26.0) | <0.001 | |
Smoking history | ||||
No | 143 (90.5) | 115 (74.7) | ||
Former | 10 (6.3) | 20 (13.0) | ||
Current | 5 (3.2) | 19 (12.3) | 0.011 | |
SBP (mmHg) | 114.8 (13.2) | 123.7 (15.2) | <0.001 | |
DBP (mmHg) | 69.4 (8.3) | 75.0 (9.6) | <0.001 | |
AST (IU/L) | 19.6 (7.3) | 39.8 (17.4) | <0.001 | |
ALT (IU/L) | 19.4 (10.6) | 72.2 (41.3) | <0.001 | |
GGT (IU/L) | 18.3 (8.5) | 58.8 (31.7) | <0.001 | |
Steatosis | ||||
Grade 0 | - | |||
Grade 1 | 40 (26.0) | |||
Grade 2 | 83 (53.9) | |||
Grade 3 | 31 (20.1) | |||
Necroinflammation | ||||
Grade 0 | 48 (31.2) | |||
Grade 1 | 58 (37.7) | |||
Grade 2 | 46 (29.8) | |||
Grade 3 | 2 (1.3) | |||
Fibrosis | ||||
Stage 0 | 88 (57.2) | |||
Stage 1 | 59 (38.3) | |||
Stage 2 | 7 (4.5) | |||
Stage 3 | - | |||
Stage 4 | - |
Variables presented as mean (SD) or number (%); BMI: body mass index, SBP: systolic blood pressure; DBP: diastolic blood pressure, AST: aspartate aminotransferase; ALT, alanine aminotransferase; GGT: gamma glutamyl transferase.