Table 2. Distribution of resistin gene (RETN) rs1862513 polymorphism in the patients with nonalcoholic fatty liver and in the controlsa.
RETN (rs1862513) | Controls (n=154) | Patients (n=150) | Crude OR (95%CI) p-value | Adjusted OR (95%CI) p-valueb | |
---|---|---|---|---|---|
Genotype-wise comparison | |||||
GG | 73 (47.4) | 86 (57.3) | 1.0 (reference) | 1.0 (reference) | |
GC | 43 (27.9) | 37 (24.7) | 0.87 (0.71–1.58)0.750 | 0.92 (0.67–1.60)0.890 | |
CC | 38 (24.7) | 27 (18.0) | 0.43 (0.41–0.88)0.028 | 0.47 (0.36–0.93)0.030 | |
GC and CC | 81 (52.6) | 64 (42.7) | 0.72 (0.64–1.20)0.207 | 0.77 (0.6–1.21)0.219 | |
CC versus others | 38 (24.7) | 27 (18.0) | 0.61 (0.59–1.23)0.052 | 0.64 (0.5–1.27)0.056 | |
Allele-wise comparison | |||||
G | 189 (61.4) | 209 (69.7) | 1.0 (reference) | – | |
C | 119 (38.6) | 91 (30.3) | 0.72 (0.53–0.95)0.042 | – |
Variables presented as numbers (%).
Adjusted for age, body mass index, sex, smoking status, systolic blood pressure, and diastolic blood pressure in genotype-wise comparisons.