Table 1.
Demographic and clinical data of the study cohort (n = 62).
| No GM/ IVH (n = 34) | GM/ IVH (n = 28) | p value | |
|---|---|---|---|
| GA (weeks) | 26.1 (25.3–27.1) | 25.1 (24.1–26.1) | 0.0180a |
| Birth weight (g) | 805 (690–930) | 697.5 (582.5–858.5) | 0.1431 |
| Multiple Births | 11 (32.4) | 6 (21.4) | 0.3373 |
| Sex (male) | 14 (41.2) | 18 (64.3) | 0.0700 |
| Chorioamnionitis | 3 (8.8) | 6 (21.4) | 0.2773 |
| Cesarean section | 30 (88.2) | 20 (71.4) | 0.1165 |
| Apgar 1 min | 4.0 (3.0–6.0) | 3.0 (1.5–5.0) | 0.0641 |
| Apgar 5 min | 7.0 (6.0–8.0) | 6.0 (4.0–7.5) | 0.1414 |
| Chest compressions in DR | 3 (8.8) | 3 (10.7) | 1.0000 |
| Baseline Base deficit (mEq/L) | 2.5 (1.4–4.4) | 3.5 (1.8–5.6) | 0.2211 |
| Baseline pCO2 (mmHg) | 48.8 (43.2–53.7) | 50.2 (43.1–55.3) | 0.5812 |
| Baseline Hematocrit (%) | 44.4 (39.0–47.8) | 40.0 (35.8–45.3) | 0.0351a |
| Intubated | 10 (29.4) | 19 (67.9) | 0.0025a |
| PDA | 24 (70.6) | 20 (71.4) | 0.9422 |
| Sepsis | 2 (5.9) | 8 (28.6) | 0.0334a |
| ROPb | 19/32 (59.4) | 20/22 (90.9) | 0.0139a |
| Death | 1 (2.9) | 4 (14.3) | 0.1658 |
| HOL until first detection of hemorrhage | N/A | 41.2 (18.7–66.2) | 0.9795 |
| HOL NIRS measurements began | 9.5 (5–19) | 7 (4.5–18.5) | 0.6099 |
| HOL NIRS measurements ended | 80.5 (73–100) | 78 (67.5–126.5) | 0.9211 |
| Median duration (hours) of measurement | 68 (54–89) | 70 (48–109) | 0.5714 |
Categorical and binary data presented as n (%), continuous data as medians (Interquartile range (IQR)).
Differences among categories were assessed using chi-square (exact for tests of small sample size, n < 5), Wilcoxon rank sum.
GA gestational age, DR delivery room, PDA Patent Ductus Arteriosus, ROP Retinopathy of Prematurity.
a
p value < 0.05.
b
Not all subjects had data on ROP status. In the Table we have specified the denominator for this variable to provide the total number of subjects on which our percentages are based.