FIG. 5.

Growth curves for RCΔ97.19 in HEL and HEL97 cells. HEL cells and HEL97 cells were infected with either RCΔ97.19 or AD169 at an MOI of approximately 0.1 PFU/cell, and infected monolayers were harvested at the indicated times and frozen at −80°C. Resulting progeny viruses were titered on monolayers of HEL97 cells, and titers for AD169 grown in HEL cells (●), AD169 grown in HEL97 cells ( ), RCΔ97.19 grown in HEL cells (■), and RCΔ97.19 grown in HEL97 cells (░⃞) are shown in log units of PFU per milliliter. Error bars, standard deviations of virus titers from three replicate wells.