Figure 1.

Antibody response in children with moderate and severe RSV infection. (A) Plasma levels of IgG antibodies directed to PreF protein of RSV of moderate (n=26) and severe (n=20) RSV infected infants quantified by ELISA. (B) Left: Bar graphs showing the percentage of positive samples for neutralizing activity against RSV (moderate, n=26 and severe, n=20). Right: Neutralization antibody titers against RSV determined by the reciprocal IC50 in plasma from moderate and severe RSV infants. Dotted line indicates the limit of detection value. Median and min to max of n donors are shown in A, B (right). P values were determined by Fisher’s exact test and Mann-Whitney U test. *p<0.05, ** p<0.01. UA., arbitrary units. Moderate (green circle), severe (blue circle). Negative (white square), positive (purple square).