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. 2024 Jun 27;44(7):527–540. doi: 10.1007/s40261-024-01376-w

Table 1.

Patient characteristics (safety analysis set)

Characteristic Safety analysis set
(N = 821)a
Age, years
 Median (range) 53 (4–75)
 Mean ± SD 49.75 ± 14.32
 Unknown 14 (1.71)
Sex
 Male 486 (59.20)
 Female 335 (40.80)
Number of transplants
 1 670 (81.61)
 ≥2 149 (18.15)
 Unknown 2 (0.24)
Length of hospital stay after first transplantation, daysb
 Median (range) 87.0 (17–482)
 Mean ± SD 102.3 ± 57.1
 Unknown 28 (3.41)
Primary reason for HSCT
 Acute myeloid leukemia 311 (37.88)
 Acute lymphoblastic leukemia 155 (18.88)
 Myelodysplastic syndrome 116 (14.13)
 Lymphoid malignant tumor 105 (12.79)
 Other diseases 133 (16.20)
CMV antibody combination
 R+/D+ 287 (34.96)
 R+/D− 273 (33.25)
 R−/D+ 39 (4.75)
 R−/D− 32 (3.90)
 Unknown 190 (23.14)
Stem cell source
 Cord blood 283 (34.47)
 Bone marrow 277 (33.74)
 Peripheral blood 259 (31.55)
Donor type
 Allogeneic transplantation 818 (99.63)
 Related 243 (29.60)
 Sibling 147 (17.90)
 Other sibling 88 (10.72)
 Unrelated 575 (70.04)
Autologous transplantation 1 (0.12)
 Unknown 2 (0.24)
HLA
 Matched 266 (32.40)
 Mismatched 527 (64.19)
 Mismatched excluding haploidentical 417 (50.79)
 Haploidentical 110 (13.40)
 Other 2 (0.24)
 Unknown 26 (3.17)
Conditioning regimen
 Myeloablative transplantation 389 (47.38)
 Anti-thymocyte globulin 140 (17.05)
 T-cell depletion or CD34(+) selected HSCT 9 (1.10)
 Pre-transplantation corticosteroid use 390 (47.50)
GVHD prophylaxis
 Yes 795 (96.83)
 No 2 (0.24)
 Unknown 24 (2.92)
Drugs used for GVHD prophylaxis (>5%)c
 Tacrolimus 646 (78.68)
 Methotrexate 598 (72.84)
 Mycophenolate mofetil 163 (19.85)
 Cyclosporine 139 (16.93)
 Cyclophosphamide 58 (7.06)

HSCT hematopoietic stem cell transplantation, GVHD graft versus host disease