Fig. 1.

Propensity score-matched Kaplan–Meier curves depicting the cumulative incidences of main outcomes among users of SGLT2 inhibitors and DPP-4 inhibitors. Urinary tract infection events were identified using Japanese electronic claims codes for urinary tract infections and antibiotic prescriptions. Genital bacterial infections were similarly identified. Perineal soft tissue infections include necrotizing fasciitis, cellulitis, or skin abscesses in the perineal area. Necrotizing fasciitis was defined according to the corresponding Japanese claims codes, hospitalization, and surgical treatments, such as debridement or related procedures. Cellulitis and skin abscesses were identified using the Japanese claims codes and antibiotic prescriptions. SGLT2 sodium glucose cotransporter 2, DPP-4 dipeptidyl peptidase-4, CI confidence interval