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. 2024 Jun 14;13(4):1055–1068. doi: 10.1007/s40120-024-00635-4

Table 1.

Comparison of the pump characteristics of levodopa carbidopa infusion (LCIG) and levodopa–carbidopa–entacapone (LECIG) infusion obtained from respective pump user manuals with expert inference

Smith Medical CADD 1400 legacy LCIG pump CRONO LECIG pump Comments
Size (container included) 197 × 100 mm 152 × 55 mm LECIG pump smaller
Weight (cartridge included) 500 g 230 g LECIG pump lighter
Cartridge vs syringe 100 ml cartridge (easy to attach) 47 ml pre-filled syringe Both acceptable
Flow rate 0–20 ml/h (0.1 ml/h increments) 0–20 ml/h (0.1 ml/h increments) Similar flow rates and bolus. CRONO allows multi-rate programming
Battery life Two AA alkaline batteries (approximately 14 days at 10 ml/day) 1.3 V lithium battery (90 × 47 ml infusions) Both acceptable