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. 2024 Jun 25;10(13):e33196. doi: 10.1016/j.heliyon.2024.e33196

Fig. 7.

Fig. 7

Pathway Analysis of CAF from all kidney sample.

A) ReactomeGSA gene set variation based pathway-level expression in the identified CAF. Expression values were z-score normalized by pathway.

B) Barplot generated by ReactomeGSA showing the activity of the “Organic anion transport” pathway in CAF across different samples. The horizontal axis shows the sample grouping, the vertical axis represents the expression value of the path, and the color represents the positive or negative expression value.

C) ReactomeGSA gene set variation based pathway-level expression in the CAF cluster across different tumor samples. Expression values were z-score normalized by pathway.

D) -E) Barplot generated by ReactomeGSA showing the activity of the “Regulation of thyroid hormone activity","Alanine metabolism","Conjugation of salicylate with glycine” and “Amino Acid conjugation” pathway in CAF cluster across different tumor samples. The horizontal axis shows the sample grouping, the vertical axis represents the expression value of the path, and the color represents the positive or negative expression value.