TABLE 1.
List of proteins enriched by UC2 in comparison to UC3 or UC2‐qEV.
| Symbol | Entrez gene name | Symbol | Entrez gene name |
|---|---|---|---|
| A1BG | alpha‐1‐B glycoprotein | FGG | fibrinogen gamma chain |
| A2M | alpha‐2‐macroglobulin | FN1 | fibronectin 1 |
| AFM | Afamin | GC | GC vitamin D binding protein |
| AHSG | alpha 2‐HS glycoprotein | GPX3 | glutathione peroxidase 3 |
| AMBP | alpha‐1‐microglobulin/bikunin precursor | H2BC12 | H2B clustered histone 12 |
| ANG | angiogenin | HABP2 | hyaluronan binding protein 2 |
| ANGPTL6 | angiopoietin like 6 | HPX | hemopexin |
| APCS | amyloid P component, serum | HRG | histidine rich glycoprotein |
| APOA4 | apolipoprotein A4 | IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| APOD | apolipoprotein D | IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) |
| ATXN1 | ataxin 1 | IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) |
| BANF1 | BAF nuclear assembly factor 1 | IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) |
| C1QA | complement C1q A chain | IGHV3OR16‐13 | immunoglobulin heavy variable 3/OR16‐13 (non‐functional) |
| C1QB | complement C1q B chain | IGKV1‐27 | immunoglobulin kappa variable 1‐27 |
| C1QC | complement C1q C chain | IGKV3‐7 | immunoglobulin kappa variable 3‐7 (non‐functional) |
| C1R | complement C1r | IGKV3OR2‐268 | immunoglobulin kappa variable 3/OR2‐268 (non‐functional) |
| C1RL | complement C1r subcomponent like | IGKV6‐21 | immunoglobulin kappa variable 6‐21 (non‐functional) |
| C1S | complement C1s | ITIH1 | inter‐alpha‐trypsin inhibitor heavy chain 1 |
| C2 | complement C2 | ITIH2 | inter‐alpha‐trypsin inhibitor heavy chain 2 |
| C3 | complement C3 | KNG1 | kininogen 1 |
| C4A/C4B | complement C4A (Rodgers blood group) | LPA | lipoprotein(a) |
| C4BPA | complement component 4 binding protein alpha | LRG1 | leucine rich alpha‐2‐glycoprotein 1 |
| C4BPB | complement component 4 binding protein beta | LYZ | lysozyme |
| C5 | complement C5 | MASP1 | MBL associated serine protease 1 |
| C6 | complement C6 | NGEF | neuronal guanine nucleotide exchange factor |
| C7 | complement C7 | PGLYRP2 | peptidoglycan recognition protein 2 |
| C8A | complement C8 alpha chain | PLG | plasminogen |
| C8B | complement C8 beta chain | PON1 | paraoxonase 1 |
| C8G | complement C8 gamma chain | PRG4 | proteoglycan 4 |
| C9 | complement C9 | PROS1 | protein S |
| CFH | complement factor H | PZP | PZP alpha‐2‐macroglobulin like |
| CFHR1 | complement factor H related 1 | RBP4 | retinol binding protein 4 |
| CFHR3 | complement factor H related 3 | RELN | reelin |
| CFI | complement factor I | RNASE4 | ribonuclease A family member 4 |
| CP | ceruloplasmin | SERPINA3 | serpin family A member 3 |
| CPN1 | carboxypeptidase N subunit 1 | SERPINA4 | serpin family A member 4 |
| CPN2 | carboxypeptidase N subunit 2 | SERPINA7 | serpin family A member 7 |
| ECM1 | extracellular matrix protein 1 | SERPINC1 | serpin family C member 1 |
| F12 | coagulation factor XII | SERPIND1 | serpin family D member 1 |
| F13B | coagulation factor XIII B chain | SERPINF2 | serpin family F member 2 |
| F2 | coagulation factor II, thrombin | SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| FBLN1 | fibulin 1 | TTR | transthyretin |
| FGA | fibrinogen alpha chain | VTN | vitronectin |
| FGB | fibrinogen beta chain |