. 2024 Apr 18;25(4):147. doi: 10.31083/j.rcm2504147

Table 5.

Effect of nine dominant genotypes on serum lipid levels in CAD and control groups.

SNP	Genotypes	TG	TC	HDL-C	LDL-C	ApoA	ApoB
rs1047286	CAD subgroup
	GG	2.749 $\pm$ 0.158	4.471 $\pm$ 0.045	0.984 $\pm$ 0.010	2.841 $\pm$ 0.035	1.179 $\pm$ 0.012	0.906 $\pm$ 0.012
	AA + GA	2.985 $\pm$ 0.311	4.342 $\pm$ 0.182	0.965 $\pm$ 0.034	2.712 $\pm$ 0.136	1.168 $\pm$ 0.032	0.846 $\pm$ 0.030
	p	0.389	0.472	0.608	0.361	0.755	0.069
	Control group
	GG	1.89 $\pm$ 0.049	4.15 $\pm$ 0.035	1.07 $\pm$ 0.010	2.63 $\pm$ 0.029	1.19 $\pm$ 0.009	0.85 $\pm$ 0.009
	AA + GA	1.75 $\pm$ 0.155	4.03 $\pm$ 0.120	1.12 $\pm$ 0.055	2.54 $\pm$ 0.111	1.22 $\pm$ 0.043	0.83 $\pm$ 0.034
	p	0.287	0.189	0.626	0.306	0.588	0.482
rs11569562	CAD subgroup
	GG	2.474 $\pm$ 0.956	4.392 $\pm$ 0.088	0.999 $\pm$ 0.018	2.864 $\pm$ 0.072	1.172 $\pm$ 0.018	0.904 $\pm$ 0.022
	AA + GA	2.271 $\pm$ 0.869	4.487 $\pm$ 0.051	0.977 $\pm$ 0.011	2.823 $\pm$ 0.039	1.18 $\pm$ 0.014	0.901 $\pm$ 0.014
	p	0.065	0.351	0.295	0.610	0.727	0.892
	Control group
	GG	1.96 $\pm$ 0.110	4.068 $\pm$ 0.067	1.067 $\pm$ 0.020	2.525 $\pm$ 0.052	1.198 $\pm$ 0.019	0.847 $\pm$ 0.019
	AA + GA	1.856 $\pm$ 0.051	4.168 $\pm$ 0.038	1.077 $\pm$ 0.012	2.659 $\pm$ 0.032	1.192 $\pm$ 0.010	0.852 $\pm$ 0.010
	p	0.484	0.418	0.991	0.167	0.767	0.824
rs163913	CAD subgroup
	TT	2.272 $\pm$ 0.096	4.540 $\pm$ 0.070	0.995 $\pm$ 0.015	2.872 $\pm$ 0.056	1.185 $\pm$ 0.014	0.922 $\pm$ 0.022
	CC + TC	2.159 $\pm$ 0.073	4.419 $\pm$ 0.057	0.975 $\pm$ 0.012	2.811 $\pm$ 0.043	1.174 $\pm$ 0.017	0.890 $\pm$ 0.013
	p	0.309	0.180	0.280	0.391	0.636	0.203
	Control group
	TT	1.837 $\pm$ 0.067	4.132 $\pm$ 0.050	1.069 $\pm$ 0.016	2.618 $\pm$ 0.042	1.189 $\pm$ 0.014	0.850 $\pm$ 0.014
	CC + TC	1.916 $\pm$ 0.066	4.154 $\pm$ 0.045	1.081 $\pm$ 0.014	2.632 $\pm$ 0.038	1.199 $\pm$ 0.012	0.852 $\pm$ 0.012
	p	0.314	0.700	0.577	0.786	0.598	0.937
rs2230199	CAD subgroup
	GG	2.033 $\pm$ 0.117	4.475 $\pm$ 0.046	0.983 $\pm$ 0.010	2.841 $\pm$ 0.036	1.178 $\pm$ 0.012	0.905 $\pm$ 0.013
	CC + GC	2.188 $\pm$ 0.085	4.324 $\pm$ 0.153	0.976 $\pm$ 0.036	2.737 $\pm$ 0.121	1.179 $\pm$ 0.030	0.863 $\pm$ 0.030
	p	0.207	0.349	0.854	0.410	0.971	0.190
	Control group
	GG	1.891 $\pm$ 0.050	4.152 $\pm$ 0.035	1.071 $\pm$ 0.010	2.633 $\pm$ 0.289	1.194 $\pm$ 0.009	0.853 $\pm$ 0.010
	CC + GC	1.774 $\pm$ 0.146	4.015 $\pm$ 0.114	1.111 $\pm$ 0.050	2.523 $\pm$ 0.106	1.191 $\pm$ 0.041	0.821 $\pm$ 0.032
	p	0.337	0.132	0.73	0.225	0.947	0.357
rs2230204	CAD subgroup
	TT	2.069 $\pm$ 0.135	4.643 $\pm$ 0.104	0.995 $\pm$ 0.020	2.966 $\pm$ 0.084	1.197 $\pm$ 0.023	0.933 $\pm$ 0.022
	CC + TC	2.234 $\pm$ 0.064	4.420 $\pm$ 0.048	0.979 $\pm$ 0.010	2.800 $\pm$ 0.037	1.173 $\pm$ 0.013	0.894 $\pm$ 0.014
	p	0.259	0.053	0.485	0.074	0.364	0.137
	Control group
	TT	1.896 $\pm$ 0.104	4.052 $\pm$ 0.079	1.051 $\pm$ 0.021	2.598 $\pm$ 0.064	1.188 $\pm$ 0.020	0.865 $\pm$ 0.023
	CC + TC	1.879 $\pm$ 0.053	4.164 $\pm$ 0.037	1.080 $\pm$ 0.012	2.631 $\pm$ 0.031	1.195 $\pm$ 0.010	0.847 $\pm$ 0.001
	p	0.893	0.175	0.186	0.567	0.755	0.466
rs2241393	CAD subgroup
	GG	2.347 $\pm$ 0.105	4.484 $\pm$ 0.115	0.999 $\pm$ 0.256	2.761 $\pm$ 0.084	1.211 $\pm$ 0.048	0.872 $\pm$ 0.026
	CC + GC	2.163 $\pm$ 0.080	4.460 $\pm$ 0.048	0.979 $\pm$ 0.010	2.846 $\pm$ 0.037	1.172 $\pm$ 0.010	0.927 $\pm$ 0.013
	p	0.194	0.845	0.472	0.356	0.441	0.231
	Control group
	GG	1.876 $\pm$ 0.109	4.122 $\pm$ 0.075	1.065 $\pm$ 0.026	2.598 $\pm$ 0.064	1.173 $\pm$ 0.022	0.864 $\pm$ 0.020
	CC + GC	1.884 $\pm$ 0.052	4.146 $\pm$ 0.037	1.076 $\pm$ 0.011	2.630 $\pm$ 0.031	1.197 $\pm$ 0.010	0.848 $\pm$ 0.010
	p	0.612	0.89	0.871	0.937	0.314	0.478
rs344550	CAD subgroup
	GG	2.174 $\pm$ 0.065	4.469 $\pm$ 0.069	1.004 $\pm$ 0.015	2.842 $\pm$ 0.054	1.182 $\pm$ 0.014	0.907 $\pm$ 0.016
	CC + GC	2.307 $\pm$ 0.127	4.460 $\pm$ 0.057	0.968 $\pm$ 0.012	2.827 $\pm$ 0.044	1.176 $\pm$ 0.017	0.899 $\pm$ 0.016
	p	0.576	0.920	0.056	0.824	0.790	0.723
	Control group
	GG	1.992 $\pm$ 0.090	4.109 $\pm$ 0.054	1.085 $\pm$ 0.018	2.563 $\pm$ 0.043	1.204 $\pm$ 0.015	0.853 $\pm$ 0.015
	CC + GC	1.815 $\pm$ 0.052	4.162 $\pm$ 0.042	1.068 $\pm$ 0.013	2.663 $\pm$ 0.365	1.187 $\pm$ 0.011	0.849 $\pm$ 0.011
	p	0.078	0.709	0.241	0.209	0.375	0.817
rs7257062	CAD subgroup
	TT	2.059 $\pm$ 1.447	4.473 $\pm$ 1.329	0.976 $\pm$ 0.262	2.872 $\pm$ 1.080	1.174 $\pm$ 0.267	0.906 $\pm$ 0.318
	CC + TC	2.326 $\pm$ 1.889	4.454 $\pm$ 1.259	0.987 $\pm$ 0.278	2.800 $\pm$ 0.937	1.180 $\pm$ 0.385	0.898 $\pm$ 0.371
	p	0.019*	0.833	0.566	0.304	0.779	0.749
	Control group
	TT	1.913 $\pm$ 0.070	4.128 $\pm$ 0.051	1.066 $\pm$ 0.015	2.615 $\pm$ 0.041	1.187 $\pm$ 0.013	0.851 $\pm$ 0.014
	CC + TC	1.851 $\pm$ 0.062	4.156 $\pm$ 0.043	1.083 $\pm$ 0.015	2.635 $\pm$ 0.038	1.200 $\pm$ 0.012	0.850 $\pm$ 0.012
	p	0.382	0.584	0.395	0.590	0.478	0.951
rs8107911	CAD subgroup
	GG	2.456 $\pm$ 0.502	4.226 $\pm$ 0.263	0.918 $\pm$ 0.050	2.649 $\pm$ 0.234	1.106 $\pm$ 0.054	0.836 $\pm$ 0.059
	AA + GA	2.199 $\pm$ 0.058	4.466 $\pm$ 0.044	0.983 $\pm$ 0.009	2.835 $\pm$ 0.035	1.179 $\pm$ 0.012	0.903 $\pm$ 0.012
	p	0.628	0.389	0.226	0.449	0.213	0.294
	Control group
	GG	1.668 $\pm$ 0.375	4.129 $\pm$ 0.168	2.574 $\pm$ 0.176	1.294 $\pm$ 0.076	0.803 $\pm$ 0.064	0.803 $\pm$ 0.064
	AA + GA	1.886 $\pm$ 0.048	4.142 $\pm$ 0.034	1.071 $\pm$ 0.010	2.626 $\pm$ 0.028	1.192 $\pm$ 0.009	0.851 $\pm$ 0.009
	p	0.611	0.901	0.065	0.745	0.209	0.466

*: p $<$ 0.05. SNP, single nucleotide polymorphism; CAD, coronary artery disease; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; TC, total cholesterol; TG, triglyceride; ApoA, apolipoprotein A; ApoB, apolipoprotein B.