TABLE 3.
Alanine scan on peptide 12p1
| Peptide sequence | IC50 (μM)a |
|---|---|
| 2dCD4 | 8.7 ± 2.1 nM (13) |
| R-I-N-N-I-P-W-S-E-A-M-M | 25.7 ± 7.3 (13) |
| A-I-N-N-I-P-W-S-E-A-M-M | 9 |
| R-A-N-N-I-P-W-S-E-A-M-M | 300 |
| R-I-A-N-I-P-W-S-E-A-M-M | >500 |
| R-I-N-A-I-P-W-S-E-A-M-M | >500 |
| R-I-N-N-A-P-W-S-E-A-M-M | >500 |
| R-I-N-N-I-A-W-S-E-A-M-M | >500 |
| R-I-N-N-I-P-A-S-E-A-M-M | >500 |
| R-I-N-N-I-P-W-A-E-A-M-M | >500 |
| R-I-N-N-I-P-W-S-A-A-M-M | 43 |
| R-I-N-N-I-P-W-S-E-A-A-M | 15 |
| R-I-N-N-I-P-W-S-E-A-M-A | 55 |
a
Values are means ± standard errors; the number of experiments is given in parentheses.