Table 2.

Logistic regression analysis for the risk of stroke according to SII in the overall NHANES participant group.

Model	Per one unit increase in log-transformed SII OR (95% CI)	OR (95% CI)
		Low	Median	High	p trend
Crude	1.98 (1.47, 2.66)	1.00	1.16 (0.97, 1.37)	1.46 (1.23, 1.74)	0.001
Model 1	1.54 (1.17, 2.03)	1.00	1.14 (0.96, 1.36)	1.32 (1.11, 1.58)	0.002
Model 2	1.34 (1.02, 1.76)	1.00	1.11 (0.93, 1.33)	1.22 (1.02, 1.47)	0.028
Model 3	1.30 (0.99, 1.70)	1.00	1.10 (0.92, 1.31)	1.18 (1.01, 1.42)	0.041

Model 1: adjusted for age, sex, and race/ethnicity; Model 2: further adjusted (from Model 1) for smoking status, physical activity, education level, family income to poverty ratio, and BMI; Model 3: further adjusted (from Model 2) for diabetes, dyslipidemia, cancer, and hypertension. OR, odds ratio; CI, confidence interval; BMI, body mass index; SII, systemic immune-inflammation index; NHANES, National Health and Nutrition Examination Survey.