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. 2021 Mar 21;20(3):713–718. doi: 10.5114/aoms/118938

Table III.

Echocardiographic parameters based on aortic valve area

Parameter Moderately severe AS (AVA 0.8–0.99 cm2) (n = 75) (1) Severe AS (AVA 0.60–0.79 cm2) (n = 90) (2) Critical AS (AVA ≤ 0.59 cm2) (n = 35) (3) P-values comparing columns
1 vs. 2 1 vs. 3
Ejection fraction (%) 57 ±13 58 ±15 52 ±15 0.64 0.11
Aortic valve area [cm2] 0.86 ±0.04 0.69 ±0.05 0.46 ±0.08 < 0.001 < 0.001
Peak gradient [mm Hg] 42 ±18 61 ±22 71 ±30 < 0.001 < 0.001
Mean gradient [mm Hg] 24 ±11 37 ±15 43 ±19 < 0.001 < 0.001
EDV [ml] 85 ±33 95 ±43 86 ±30 0.12 0.95
SV biplane [ml] 48 ±13 52 ±16 42 ±12 0.08 0.03
SV LVOT [ml] 51 ±15 54 ±14 41 ±9 0.22 < 0.001
SV index (LVOT) 30 ±9 31 ±8 25 ±6 0.67 0.002
Ejection time [ms] 304 ±40 319 ±30 322 ±30 0.02 0.05
MSF [ml/s] 169 ±41 171 ±44 129 ±29 0.79 < 0.001
LVOT diameter [cm] 1.8 ±0.21 1.8 ±0.23 1.74 ±0.18 0.27 0.10
Heart rate [beats/min] 73 ±12 74 ±14 75 ±13 0.43 .040

n – number of subjects, AVA – aortic valve area, EDV – end diastolic volume, SV biplane – stroke volume biplane Simpson’s method, LVOT – left ventricular outflow tract, MSF – mean systolic flow.