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. 2024 Jun 28;20(3):984–996. doi: 10.5114/aoms/174264

Figure 4.

Figure 4

Figure 4

Ondansetron inhibits TREM-1 expression in alveolar macrophages. A – TREM-1 staining of bronchioles and alveoli in histology sections. Scale bar = 50 μm, N = 4. B – sTREM-1 plasma levels in sham group, TBI + NS group, and TBI + OD group. N = 4. C – TREM-1 mRNA expression after OD administration. N = 4. ***P < 0.001 vs. sham group. ###P < 0.001 vs. TBI + NS group. D – Representative images of isolated AMs in BALF after immunostaining for CD68 and TREM-1. Scale bar = 50 μm. N = 3.The values are presented as mean ± standard deviation. ***P < 0.001 vs. sham group. ###P < 0.001 vs. TBI + NS group