Table I.
Characteristics of the study population – newborns from diabetic (D) and normal pregnancies (R)
| Parameter | Diabetes (D) (n = 50) | Reference group (R) (n = 88) | P-value |
|---|---|---|---|
| Median (Q1–Q3) | |||
| Gestational age [weeks] | 39 (38–39) | 39 (39–40) | 0.0002 |
| Gender (boys/girls) | 33/17 | 44/44 | 0.069 |
| Birth weight [g] | 3400 (3000–3860) | 3450 (3165–3800) | NS |
| Length [cm] | 56 (54–58) | 56 (54–57) | NS |
| Head circuit [cm] | 34 (33–35) | 34 (33–35) | NS |
| Chest circuit [cm] | 33 (32–35) | 34 (33–35) | NS |
| uNGAL [ng/ml] | 25.74 (11.84–40.81) | 16.74 (9.99–27.47) | 0.015 |
| uNGAL/creatinine [ng/mg cr.] | 29.12 (19.12–47.41) | 21.91 (14.57–29.77) | 0.007 |
| uKIM-1 [ng/ml] | 1.43 (0.80–4.64) | 1.29 (0.63–2.52) | NS |
| uKIM-1/creatinine [ng/mg cr.] | 2.23 (1.09–4.09) | 1.87 (0.84–3.26) | NS |
| Serum creatinine [mg/dl] | 0.67 (0.56–0.83) | 0.61 (0.54–0.70) | NS |
| eGFR [ml/min/1.73 m2] | 37.85 (29.30–43.60) | 40.15 (35.00–46.70) | NS |
uNGAL – urine neutrophil gelatinase-associated lipocalin, uKIM-1 – urine kidney injury molecule-1, cr. – creatinine, eGFR – estimated glomerular filtration rate, p – diabetes – reference group.