Table II.
Comparison of examined parameters in subgroups on diet (D1) and on insulin therapy (D2) with the reference group (R)
| Parameter | Diabetes (D1) (n = 22) | Diabetes (D2) (n = 28) | Reference(R) (n = 44) | P-value1 | P-value2 |
|---|---|---|---|---|---|
| Median (Q1–Q3) | |||||
| Gestational age [weeks] | 39 (38–40) | 38 (37.5–39) | 39 (39–40) | 0.045 | 0.0002 |
| Gender (boys/girls) | 14/8 | 19/9 | 44/44 | 0.251 | 0.098 |
| Birth weight [g] | 3300 (3020–3750) | 3520 (3000–3865) | 3450 (3165–3800) | NS | NS |
| Length [cm] | 56 (54–58) | 56 (54–57.5) | 56 (54–57) | NS | NS |
| Head circuit [cm] | 34 (32–35) | 33.5 (33–35) | 34 (33–35) | NS | NS |
| Chest circuit [cm] | 33.5 (32–35) | 33 (32–35) | 34 (33–35) | NS | NS |
| uNGAL [ng/ml] | 25.15 (11.61–39.54) | 27.78 (13.58–44.27) | 16.74 (9.99–27.47) | NS | 0.010 |
| uNGAL/creatinine [ng/mg cr.] | 26.30 (20.22–44.34) | 31.88 (17.63–57.42) | 21.91 (14.57–29.77) | NS | 0.022 |
| uKIM-1 [ng/ml] | 1.08 (0.57–2.08) | 1.758 (0.88–5.66) | 1.289 (0.63–2.52) | NS | NS |
| uKIM-1/creatinine [ng/mg cr.] | 1.41 (1.03–2.99) | 2.64 (1.58–5.56) | 1.87 (0.84–3.26) | NS | 0.019 |
| Serum creatinine [mg/dl] | 0.64 (0.51–0.71) | 0.70 (0.60–0.90) | 0.61 (0.54–0.70) | NS | NS |
| eGFR [ml/min/1.73 m2] | 41.30 (36.80–49.70) | 36.30 (27.75–41.90) | 40.15 (35.00–46.70) | NS | NS |
uNGAL – urine neutrophil gelatinase-associated lipocalin, uKIM-1 – urine kidney injury molecule-1, cr. – creatinine, eGFR – estimated glomerular filtration rate, p1 – diabetes (D1) – reference group, p2 –diabetes (D2) – reference group.