TABLE 3.
Stillbirths by variant predominance period
| Total, N (%) | Pre-delta, n (%) (March 3,2020-June 26,2021) | Delta, n (%) (June 27, 2021-Dec. 25, 2021) | ||
|---|---|---|---|---|
| Stillbirtha | Total | 310 (100.0) | 177 (57.1) | 133 (42.9) |
| Gestational age | (Median, IQR) | 29.4 (23.0–34.9) | 30.0 (23.5–35.6) | 27.9 (22.5–33.4) |
| Days from maternal PCR+ to stillbirth | (Median, IQR) | 18 (2–94) | 29 (1–100) | 13 (4–64) |
| Days from maternal PCR+ to stillbirth by trimester of infection | First (Median, IQR) | 124 (95–164) | 125 (94.3–170) | 124 (97–146) |
| Second (Median, IQR) | 15 (2–57) | 19 (2–67) | 11 (3–33) | |
| Third (Median, IQR) | 4 (1–12) | 1 (0–12) | 7 (1–12) | |
| Trimester of infection | First | 77 (24.8) | 48 (27.1) | 29 (21.8) |
| Second | 136 (43.9) | 76 (42.9) | 60 (45.1) | |
| Third | 97 (31.3) | 53 (29.9) | 44 (33.1) | |
| Delivery type | Vaginal | 257 (82.9) | 145 (81.9) | 112 (84.2) |
| Cesarean delivery | 44 (14.2) | 27 (15.3) | 17 (12.8) | |
| Unknown | 9 (2.9) | 5 (2.8) | 4 (3.0) | |
| Induction | Induced | 51 (16.5) | 36 (20.3) | 15 (11.3) |
| Not induced | 50 (16.1) | 30 (16.9) | 20 (15.0) | |
| Unknown | 209 (67.4) | 111 (62.7) | 98 (73.7) | |
| Pre-pregnancy obesity | Yes | 106 (34.2) | 64 (36.2) | 42 (31.6) |
| No | 151 (48.7) | 78 (44.1) | 73 (54.9) | |
| Unknown | 53 (17.1) | 35 (19.8) | 18 (13.5) | |
| Gestational diabetes | Yes | 25 (8.1) | 14 (7.9) | 11 (8.3) |
| No | 237 (76.5) | 144 (81.4) | 93 (69.9) | |
| Unknown | 48 (15.5) | 19 (10.7) | 29 (21.8) | |
| Pregnancy-induced hypertension | Yes | 26 (8.4) | 18 (10.2) | 8 (6.0) |
| No | 215 (69.4) | 117 (66.1) | 98 (73.7) | |
| Unknown | 69 (22.3) | 42 (23.7) | 27 (20.3) | |
| Other underlying conditionb | Yes | 138 (44.5) | 82 (46.3) | 56 (42.1) |
| No | 154 (49.7) | 89 (50.3) | 65 (48.9) | |
| Unknown | 18 (5.8) | 6 (3.4) | 12 (9.0) |
IQR, interquartile range; PCR, polymerase chain reaction.
a
Row percent for total; remaining table includes column percent.;
b
Includes pre-pregnancy diabetes, chronic hypertension, chronic lung disease, cardiovascular disease, renal disease, liver disease, autoimmune condition, immunosuppressive condition, and disability.