Fig. 1.

Moderating effects of thyroid hormones on the relationships between Aβ and tau deposition. Notes: To effectively demonstrate the moderating effects, participants were divided into two subgroups based on thyroid hormone levels. Each line represents a regression line for IT tau deposition, with global Aβ deposition as the independent variable, controlling for age, sex, and APOE ε4 positivity. The shaded regions demonstrate the 95% confidence intervals of the regression lines. Abbreviations: Aβ beta-amyloid, IT inferior temporal, SUVR standardized uptake value ratio, T3 triiodothyronine, T4 thyroxine, APOE Apolipoprotein E