Table 4.

Relationship between Aβ and tau deposition in subgroups based on thyroid hormone levels (n = 74)

	B (95% CI)	SE	R2	p-value
Low fT4 (fT4 < 1.12)	0.326 (-0.001–0.653)	0.161	0.182	0.051
High fT4 (fT4 ≥ 1.12)	0.547 (0.353–0.742)	0.096	0.611	0.000
Low fT3 (fT3 < 3.05)	0.173 (-0.076–0.421)	0.122	0.215	0.167
High fT3 (fT3 ≥ 3.05)	0.694 (0.499–0.889)	0.096	0.659	0.000

Notes: Multiple linear regression models for IT tau deposition included global Aβ deposition as an independent variable, after adjusting for age, sex, and APOE ε4 positivity

Abbreviations: Aβ beta-amyloid, T3 triiodothyronine, T4 thyroxine, IT inferior temporal, APOE Apolipoprotein E, CI confidence interval, SE standard error