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. 2024 Jun 7;11(4):927–945. doi: 10.1007/s40744-024-00672-3

Table 2.

The patient journey to axial spondyloarthritis diagnosis stratified by region

Mean ± SD or n (%) p value
Europe North America Latin America Asia South Africa
Diagnostic delay, n = 5327 7.7 ± 8.8 9.0 ± 11.0 5.9 ± 8.6 4.2 ± 5.4 10.8 ± 10.6  < 0.001
HCP seen before diagnosis, n = 5328
GP 2731 (82.5) 650 (86.1) 385 (70.5) 258 (44.9) 117 (83.0)  < 0.001
Rheumatologist 1959 (59.2) 350 (46.4) 213 (39.0) 164 (28.5) 45 (31.9)
Orthopaedic specialist 1143 (34.5) 178 (23.6) 332 (60.8) 374 (65.0) 48 (34.0)
Physiotherapist 1309 (39.5) 350 (46.4) 169 (31.0) 104 (18.1) 16 (11.3)
Osteopath 519 (15.7) 74 (9.8) 46 (8.4) 11 (1.9) 5 (3.5)
Other 441 (13.3) 99 (13.1) 66 (12.1) 18 (3.1) 18 (12.8)
Chiropractor 285 (8.6) 274 (36.3) 11 (2.0) 53 (9.2) 43 (30.5)
HCP that made diagnosis, n = 5326
Rheumatologist 2499 (76.5) 511 (66.4) 407 (74.3) 323 (53.9) 102 (70.8)  < 0.001
GP 413 (12.6) 151 (19.6) 78 (14.2) 48 (8.0) 18 (12.5)
Orthopaedic specialist 187 (5.7) 39 (5.1) 42 (7.7) 203 (33.9) 11 (7.6)
Other 130 (4.0) 49 (6.4) 18 (3.3) 14 (2.3) 13 (9.0)
Physiotherapist 36 (1.1) 20 (2.6) 3 (0.5) 11 (1.8) 0 (0.0)
First test for diagnosis, n = 4619
X-ray 2047 (69.5) 470 (73.6) 136 (33.3) 267 (52.7) 44 (36.7)  < 0.001
HLA-B27 2000 (67.9) 440 (68.9) 273 (66.9) 312 (61.5) 95 (79.2)
MRI scan 1825 (62.0) 430 (67.3) 142 (34.8) 295 (58.2) 40 (33.3)
CT scan 603 (20.3) 196 (30.7) 105 (25.7) 145 (28.6) 21 (17.5)
Ultrasound 577 (19.6) 173 (27.1) 67 (16.4) 114 (22.5) 16 (13.3)
Radionuclide scintigraphy 430 (14.6) 100 (15.6) 78 (19.1) 61 (12.0) 10 (8.3)
Other 125 (4.2) 61 (9.5) 20 (4.9) 11 (2.2) 12 (10.0)

SD standard deviation, HCP healthcare professional, GP general practitioner, HLA-B27 human leukocyte antigen (HLA) B27, MRI magnetic resonance imaging, CT computed tomography