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. 2024 Jul 22;24:250. doi: 10.1186/s12883-024-03761-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Brain MRI of the three cases. Case 1: Initial MRI with periventricular T2/FLAIR hyperintensities (A, C) and nodular gadolinium enhancement (B, D). Case 2: Brain MRI with T2/FLAIR hyperintensities of the corpus callosum extending to the corona radiata (E), of the right parieto-occipital subcortical white matter (G) and of the bilateral pyramids (F). Spinal MRI with bilateral lateral columns T2 hyperintensities (H). Case 3: Brain MRI with T2 hyperintense fronto-sagittal lesion and perilesional edema (I) and strong gadolinium enhancement (J)