Table 7.
Top 10 Gene Ontology (GO) Biological Processes enriched with ToppFun in ToppGene Suite
| GO ID | GO Biological | Bonferroni | Genes |
|---|---|---|---|
| Process | P-value | ||
| GO:0001944 | Vasculature development | 2.71E-10 | DAB2,EPHB3,SLIT2,BIRC5,TCF4,THBS2,SPARC,MMP2 |
| TNFRSF1B,THY1,DCN,IGFBP7,PDGFRB,LOX,HLA-F,COL1A2 | |||
| GO:0001568 | Blood vessel development | 2.10E-09 | DAB2,EPHB3,SLIT2,BIRC5,TCF4,THBS2,SPARC,MMP2 |
| THY1,DCN,IGFBP7,PDGFRB,LOX,HLA-F,COL1A2 | |||
| GO:0048514 | Blood vessel morphogenesis | 9.21E-09 | DAB2,EPHB3,SLIT2,BIRC5,TCF4,THBS2,SPARC,MMP2 |
| THY1,DCN,IGFBP7,PDGFRB,LOX,HLA-F | |||
| GO:0030198 | Extracellular matrix organization | 1.40E-08 | COL6A1,MFAP4,SPARC,MMP2,TNFRSF1B |
| DCN,TIMP2,LOX,VCAN,BGN,COL1A2 | |||
| GO:0043062 | Extracellular structure organization | 1.43E-08 | COL6A1,MFAP4,SPARC,MMP2,TNFRSF1B |
| DCN,TIMP2,LOX,VCAN,BGN,COL1A2 | |||
| GO:0045229 | External encapsulating structure organization | 1.53E-08 | COL6A1,MFAP4,SPARC,MMP2,TNFRSF1B |
| DCN,TIMP2,LOX,VCAN,BGN,COL1A2 | |||
| GO:0072359 | Circulatory system development | 1.83E-08 | DAB2,EPHB3,SLIT2,BIRC5,TCF4,THBS2,SPARC,MMP2,TNFRSF1B |
| THY1,DCN,IGFBP7,PDGFRB,LOX,VCAN,HLA-F,COL1A2 | |||
| GO:0001525 | Angiogenesis | 2.46E-08 | DAB2,EPHB3,SLIT2,BIRC5,TCF4,THBS2,SPARC |
| MMP2,THY1,DCN,IGFBP7,PDGFRB,HLA-F | |||
| GO:0035295 | Tube development | 1.39E-07 | DAB2,EPHB3,SLIT2,SPDEF,BIRC5,TCF4,THBS2,SPARC,MMP2 |
| THY1,DCN,IGFBP7,PDGFRB,LOX,VCAN,HLA-F | |||
| GO:0035239 | Tube morphogenesis | 1.02E-06 |
DAB2,EPHB3,SLIT2,BIRC5,TCF4,THBS2,SPARC,MMP2 THY1,DCN,IGFBP7,PDGFRB,LOX,HLA-F |