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. 2024 Feb 14;25:69. doi: 10.1186/s12859-024-05679-9

Table 9.

Genes corresponding to CpG sites. Top 10 Pathways enriched with ToppFun in ToppGene Suite

ID Pathway Source Bonferroni
P-value
Genes
M12868 Pathways in cancer MSigDB C2 BIOCARTA 0.001107 TGFB3,FGF2,WNT2,RASSF1,RARA
M39427 Pluripotent stem cell differentiation pathway MSigDB C2 BIOCARTA 0.002385 TGFB3,FGF2,WNT2
83105 Pathways in cancer BioSystems: KEGG 0.002876 TGFB3,FGF2,WNT2,RASSF1,RARA
M5889 Ensemble of genes encoding extracellular MSigDB C2 BIOCARTA 0.02151 ADAMTS12,IGFBP7,TGFB3
matrix and extracellular IL1RN,FGF2,WNT2
matrix-associated proteins
M5883 Genes encoding secreted soluble factors MSigDB C2 BIOCARTA 0.04072 TGFB3,IL1RN,FGF2,WNT2
M5885 Ensemble of genes encoding ECM-associated MSigDB C2 BIOCARTA 0.06319 ADAMTS12,TGFB3,IL1RN,
proteins including ECM-affilaited proteins, FGF2,WNT2
ECM regulators
and secreted factors
138010 Glypican 1 network BioSystems: Pathway Interaction 0.06838 TGFB3,FGF2
Database
M33 Glypican 1 network MSigDB C2 BIOCARTA 0.07382 TGFB3,FGF2
749777 Hippo signaling pathway BioSystems: KEGG 0.07853 TGFB3,WNT2,RASSF1
M12095 Signal transduction through IL1R MSigDB C2 BIOCARTA 0.09762 TGFB3,IL1RN