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. 2024 Jul 22;22:432. doi: 10.1186/s12951-024-02722-y

Fig. 7.

Fig. 7

Analysis of of inflammatory pathways. (a) the levels of ra biomarkers in serum (crp, ccp-ab, ana, and rf-ab). (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). (b) Serum concentration of pro-inflammatory cytokines (tnf-α、il-12、il-1β、ifn-γ andil-17a). (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). (c) if confirmed the expression level of akt, nf-κb and il-1β. Scale bars: 100 μm. (d) comparison of if expression levels among different groups. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)