Table 2.

Primary, secondary, and exploratory outcomes. Values are number with outcome/total number in group (percentage) unless stated otherwise

Outcomes*	CDSS group	Usual care group	Intervention effect (95% CI)	P value
Primary outcome
Visits with appropriate treatment	17 975/23 113 (77.8)	17 328/27 868 (62.2)	15.2 (10.7 to 19.8)†	<0.001
Secondary outcomes
Visits with acceptable appropriate treatment	19 581/23 113 (84.7)	19 622/27 868 (70.4)	12.6 (8.1 to 17.2)†	<0.001
Mean (SD) change in systolic blood pressure (mm Hg)	−1.5 (16.2)	0.3 (16.1)	−1.6 (−2.7 to −0.5)‡	0.006
Blood pressure controlled at 9 months (<140/90 mm Hg)	3415/4952 (69.0)	3778/5845 (64.6)	4.4 (−0.7 to 9.5)†	0.07
Exploratory outcome
Vascular events	59/5755 (1.0)	44/6382 (0.7)	0.1 (−0.3 to 0.5)†	0.43

CDSS=clinical decision support system; CI=confidence interval; SD=standard deviation.

^*For visit level analysis (appropriate or acceptable treatment), both practice and participant were included as random intercepts. For other participant level analysis, practice was included as random intercepts. The region, baseline appropriate antihypertensive treatment rate (≥median or <median), and calendar time were included as fixed effects in all models.

^†Absolute difference (percentage points).

^‡Mean change in blood pressure.