Table 1. Baseline characteristics of 102 neonates included in the study.
Continuous variables are expressed as median (interquartile interval). Categorical variables are expressed in absolute count (percentage).
*Comparison between the control group and the total sepsis group.
**Comparison of the early-onset sepsis group versus the late-onset sepsis group.
| Variable | Total (N = 102) | Sepsis (N = 55) | No sepsis (N = 47) | P-value* | |||
| Total | EOS (n = 28) | LOS (n = 27) | P-value** | ||||
| GA at delivery, median (IQR) | 34 (5) | 34 (5.5) | 34 (6) | 35 (6) | 0.28 | 35 (5.5) | 0.22 |
| Infant weight (g), median (IQR) | 2200 (1007.5) | 2300 (1145.0) | 2315 (1347.5) | 2300 (1120) | 0.89 | 2100.0 (800) | 0.65 |
| Male gender, n (%) | 70 (68.62) | 43 (78.18) | 22 (78.6) | 21 (77.8) | 0.99 | 27 (57.44) | 0.18 |
| Cesarean birth, n (%) | 36 (35.29) | 29 (52.72) | 14 (50) | 15 (55.6) | 0.78 | 7 (14.89) | <0.001 |
| Preterm birth, n (%) | 84 (17.64) | 49 (89.09) | 27 (96.4) | 22 (81.5) | 0.10 | 35 (74.46) | 0.06 |
| Fetal growth restriction, n (%) | 41 (40.19) | 17 (30.90) | 7 (25.0) | 10 (37) | 0.39 | 24 (51.06) | 0.04 |
| APGAR score at 1 minute, median (IQR) | 7 (2) | 7 (3) | 7 (4) | 7 (2) | 0.20 | 7 (1) | 0.57 |
| D-dimer (ng/mL), median (IQR) | 364 (1434.75) | 1560 (1987) | 1871.5 (2179.0) | 1217.0 (2022) | 0.30 | 220 (93) | <0.001 |
| Maternal characteristics | |||||||
| Parity, median (IQR) | 2 (2) | 2 (2.5) | 2 (3) | 2 (2) | 0.47 | 2 (1) | 0.34 |
| Pregnancy-induced hypertension, n (%) | 4 (3.96) | 4 (7.40) | 1 (3.6) | 3 (11.5) | 0.34 | - | NA |
| Gestational diabetes, n (%) | 1 (0.98) | - | - | - | - | 1 (2.12) | NA |
| Premature rupture of membranes, n (%) | 22 (21.56) | 17 (30.90) | 11 (39.3) | 6 (22.2) | 0.24 | 5 (10.63) | 0.01 |
| Subchorionic hemorrhage, n (%) | 17 (16.83) | 5 (9.25) | 3 (10.7) | 2 (7.4) | 0.99 | 12 (25.53) | 0.03 |
| Urinary tract infections, n (%) | 32 (31.68) | 32 (59.25) | 15 (53.6) | 17 (63) | 0.58 | - | NA |
| Positive cervical culture, n (%) | 8 (7.86) | 8 (14.54) | 5 (17.9) | 3 (11.5) | 0.70 | - | NA |
| Blood culture | |||||||
| Klebsiella, n (%) | 24 (23.5) | 24 (43.6) | 13 (46.4) | 11 (40.7) | 0.11 | - | NA |
| Escherichia coli, n (%) | 14 (13.7) | 14 (25.5) | 11 (39.3) | 3 (11.1) | NA | ||
| Staphylococcus aureus, n (%) | 1 (1.0) | 1 (1.8) | - | 1 (3.7) | - | NA | |
| Enterococcus, n (%) | 3 (2.9) | 3 (5.5) | - | 3 (11.1) | - | NA | |
| Serratia, n (%) | 8 (7.8) | 8 (14.5) | 3 (10.7) | 5 (18.5) | - | NA | |
| Enterobacter, n (%) | 3 (2.9) | 3 (5.5) | 1 (3.6) | 2 (7.4) | - | NA | |
| Pseudomonas, n (%) | 1 (1.0) | 1 (1.8) | - | 1 (3.7) | - | NA | |
| Others, n (%) | 1 (3.7) | 1 (1.8) | - | 1 (3.7) | - | NA | |