TABLE 1.
Patient characteristics.
| Characteristic | OLT recipients, N = 244 a | LUT recipients, N = 120 a |
|---|---|---|
| Sex | ||
| Females | 70 (28.7%) | 52 (43.3%) |
| Males | 174 (71.3%) | 68 (56.7%) |
| Age at vaccination (years) | 66.5 (58.5, 71.3) | 43.0 (34.8, 57.0) |
| Age at transplantation (years) | 56.2 (48.5, 62.5) | 36.0 (27.0, 51.3) |
| Time from transplantation (years) | 8.3 (3.4, 15.9) | 5.0 (4.0, 8.0) |
| BMI (kg/m2) | 25.0 (23.0, 27.0) | 22.4 (20.5, 25.7) |
| BMI category | ||
| Normal weight | 98 (40.2%) | 72 (60.0%) |
| Underweight | 3 (1.2%) | 11 (9.2%) |
| Overweight | 103 (42.2%) | 30 (25.0%) |
| Obesity | 40 (16.4%) | 7 (5.8%) |
| Indication for transplantation | ||
| Decompensated cirrhosis | 123 (50.4%) | — |
| Hepatocellular carcinoma | 116 (47.5%) | — |
| Fulminant hepatic failure | 5 (2.0%) | — |
| Cystic fibrosis | — | 75 (62.5%) |
| COPD | — | 10 (8.3%) |
| Idiopathic pulmonary fibrosis | — | 14 (11.7%) |
| Other pulmonary diseases | — | 21 (17.5%) |
| Cardiovascular disease | 37 (15.2%) | 23 (19.2%) |
| Diabetes | 82 (33.6%) | 94 (78.3%) |
| Cancer (excluding non-melanoma skin cancer) | 42 (17%) | 10 (8.3%) |
| Non-melanoma skin cancer | 9 (3.7%) | 16 (13.3%) |
| Chronic renal failure | 54 (22.1%) | 65 (54.2%) |
| Graft function | ||
| FibroScan ≥8 kPa b | 52 (21.6%) | — |
| Chronic lung allograft dysfunction | — | 31 (25.8%) |
| Previous SARS-CoV-2 infection | 12 (4.9%) | 12 (10.0%) |
| Immunosuppression regimen | ||
| Prednisone | 33 (13.5%) | 120 (100.0%) |
| Mycophenolate mofetil/Azathioprine | 168 (68.9%) | 55 (45.8%) |
| Tacrolimus/Cyclosporine | 244 (100.0%) | 120 (100.0%) |
| Triple immunosuppression | 19 (7.8%) | 91 (75.8%) |
BMI, Body mass index; COPD, Chronic obstructive pulmonary disease; OLT, Orthotopic liver transplant; LUT, Lung transplant.
a
n (%); Median (IQR).
b
Data not available in three patients.