Table 3.
KIR association effects in all anti-NMDAR cases versus controls, analyzed using a Generalized Linear Equation modeling after control of three Principal Components and iteratively controlling for significant alleles.
| Iteration | Allele | OR | Cases (n=323) | Controls (n=1519) | P-value | ||
|---|---|---|---|---|---|---|---|
| Allele* | KIR2DL4*00103 | KIR3DL3*00302 | |||||
| 1 | KIR2DL4*00103 | 1.98 | 0.254 (82) | 0.125 (190) | 6.60E-04 | N/A | N/A |
| 2 | KIR3DL3*00302 | 4.44 | 0.053 (17) | 0.013 (20) | 4.61E-04 | 2.09E-05 | N/A |
| 3 | KIR2DL1*00401 | 1.60 | 0.272 (88) | 0.185 (281) | 2.35E-02 | 1.09E-05 | 1.38E-04 |
N/A, not applicable.
*P-value corrected for multiple comparisons.