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. 2024 Jul 10;15:1433043. doi: 10.3389/fphar.2024.1433043

TABLE 2.

Stability of Q808 in Rhesus monkey plasma under various storage conditions (data was processed based on an assay of triplicate prepared QC samples at three concentrations, n = 3).

Storage conditions Spiked conc. (ng/mL) Calculated conc. (ng/mL) R.E. (%)
(mean ± SD, n = 3)
In plasma at −80°C for 30 days 2.5 2.5 ± 0.2 −0.1
22.5 20.1 ± 1.0 −10.7
600 545 ± 9.9 −9.2
In plasma after three/thaw cycles 2.5 2.4 ± 0.3 −5.9
22.5 22.1 ± 0.8 −1.8
600 561 ± 7.0 −6.5
In plasma at room temperature for 4 h 2.5 2.6 ± 0.2 2.5
22.5 24.3 ± 0.9 8
600 586 ± 26.3 −2.2
In processed samples at room temperature for 6 h 2.5 2.5 ± 0.3 −2
22.5 21.9 ± 2.9 −2.8
600 652 ± 11.4 8.7