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. 1999 Jul;73(7):6015–6023. doi: 10.1128/jvi.73.7.6015-6023.1999

FIG. 4.

FIG. 4

Principle of 18O incorporation into the internal α-carboxyl group upon proteolytic cleavage of the polypeptide chain. In the presence of 50% 18O-enriched buffer, 18O incorporation is excluded from the C-terminal peptide.