TABLE 1.
CDR3 sequences of Fabs to Ebola Zaire virus
| Fab | HCDR3 sequencea | LCDR3 sequencea |
|---|---|---|
| Library K; IgG1 κ | ||
| KZ51 | EVVVVPTAPTHNFYYYMDV | AHRGGWPLS |
| KS56, KZ52 | EGPRATGYSMADVFDI | QQYYSAPLT |
| KS14 | NEMSYDILTGPGDYYLDS | EESYSAVFT |
| KS5 | KYYSRLDV | QQYFATVWT |
| KS518 | RGSITLHREGNWFDP | QQRGNWPPIT |
| Library L; IgG1 κ | ||
| LS4 | TLSFAEVLYMDVFDI | MPGTHWPPT |
| LZ51 | TLSFAEVLYMDVFDI | QQANTFPFT |
| Library E10; IgG1 λ | ||
| ELZ510 | GYCSSTSCPPLFDS | ATWADSLSGVV |
a
HCDR3 and LCDR3 indicate heavy-chain and light-chain complementarity-determining region, respectively.