TABLE 2.
Tissue distribution of HTLV-I provirus in rats inoculated with the virus-infected cell linesa
| Cell linesb | No. of rats with HTLV-1/no. tested
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cerebrum | Cerebellum | Submandibular gland | Heart | Lung | Liver | Spleen | Kidney | Spinal cord | Bone marrow | Peripheral blood | |
| F344-S1 | 3/3 | 3/3 | 2/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 |
| TARS-1 | 0/3 | 1/3 | 1/3 | 2/3 | 3/3 | 3/3 | 1/3 | 1/3 | 2/3 | 3/3 | 2/3 |
| FPM1 | 0/3 | 3/3 | 0/3 | 0/3 | 2/3 | 1/3 | 3/3 | 2/3 | 2/3 | 0/3 | 0/3 |
a
Purified DNA from the indicated tissue was subjected to PCR amplification at 3 to 10 weeks after inoculation.
b
A total of 107 cells of each cell line were subcutaneously inoculated into nu/nu rats.