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. 2024 Jun 27;10(13):e33805. doi: 10.1016/j.heliyon.2024.e33805

Table 2.

Larvae locomotor behavior after developmental BPF and BPAF exposure. Larvae behavioral changes after embryonic exposure to BPF and BPAF performed at 120 hpf. Data shown as the fold change after normalization to the respective DMSO values (mean ± S.E; n = 3). Asterisk (*) indicates significant differences between treatments and the control at p < 0.05.



Average speed (mm/s)
Maximum acceleration (mm/s2)
Mania
Time (s)
Static time (s)
DMSO 1.00 1.00 1.00 1.00
BPF 0.01 μM 0.90 ± 0.08 1.22 ± 0.29 1.11 ± 0.11 0.96 ± 0.09
0.03 μM 1.12 ± 0.06 1.28 ± 0.18 1.37 ± 0.21 0.86 ± 0.11
0.1 μM 1.13 ± 0.10 1.18 ± 0.15 0.98 ± 0.11 0.86 ± 0.10
0.3 μM 1.38 ± 0.10* 1.52 ± 0.21* 1.26 ± 0.18 0.52 ± 0.11*
1.0 μM 1.40 ± 0.09* 1.83 ± 0.37* 1.55 ± 0.24* 0.64 ± 0.09*
BPAF 0.01 μM 1.25 ± 0.18 1.65 ± 0.26* 1.20 ± 0.24 0.88 ± 0.11
0.03 μM 1.11 ± 0.13 1.37 ± 0.18 1.26 ± 0.15 0.90 ± 0.29
0.1 μM 1.12 ± 0.14 1.30 ± 0.08 1.48 ± 0.21 0.94 ± 0.07
0.3 μM 1.62 ± 0.16* 1.74 ± 0.10* 1.59 ± 0.29* 0.70 ± 0.07*
1.0 μM 1.90 ± 0.18* 1.85 ± 0.13* 1.75 ± 0.20* 0.69 ± 0.04*