Fig. 6.

Effect of CuET on regorafenib sensitivity in MHCC-97H/REGO xenograft models in vivo.

A. Tumor volume was determined every other day. B. Mouse weight was determined every other day. C. Images of tumors harvested from nude mice after sacrifice. D. Final weights of tumors harvested from nude mice. E-F. p-ERK, vimentin, snail, E-cadherin, N-cadherin and cyclin B1 levels were visualized by immunohistochemistry. Quantitative analysis was subsequently performed. *p < 0.05, **p < 0.01, ***p < 0.001 (one-way ANOVA).