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. 2024 Apr 19;11(28):2401877. doi: 10.1002/advs.202401877

Figure 8.

Figure 8

Electrical detection of dynamics bioreaction processes. a) Monitoring of the enzyme activity of Φ29 polymerase using a thiolated biotin‐functionalized STM‐BJ. Reproduced with permission.[ 102 ] Copyright 2019, American Chemical Society. b) Monitoring of the lysozyme activity using a SWCNT FET. c) Two‐level current fluctuations of lysozyme during substrate hydrolysis. Reproduced with permission.[ 104 ] Copyright 2012, American Association for the Advancement of Science. d) Monitoring of the F1‐ATPase activity via a SiNW FET. e) Continuous recording of currents over time during F1 hydrolysis. Reproduced with permission.[ 107 ] Copyright 2017, American Chemical Society. f) Monitoring of the DNA polymerase I activity via a SWCNT FET. Reproduced with permission.[ 108b ] Copyright 2015, American Chemical Society. g) Schematic of a SiNW FET device decorated with a single PNPase molecule. h) Working principle of PNPase. i) Energy barrier in the hydrolysis of the phosphodiester bond. Reproduced under the terms of the CC‐BY license.[ 109 ] Copyright 2023, The authors, published by Springer Nature.