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Effect of colchicine treatment on the microtubules of the sciatic nerve as observed by electron microscopy. (A) Longitudinal section of the sciatic nerve of an untreated mouse. The arrows point to some of the microtubules. Magnification, ×15,470. (B) Longitudinal section of the left sciatic nerve, 1.5 days after the injection of colchicine in the left hind footpad. Note the absence of microtubules. Magnification, ×15,470. Bars, 500 nm.
