TABLE 1.

Shares of registered RWE trials reporting Random or Nonrandom Sampling and Sample Correction Procedures.

	Clinicaltrials.gov	EU‐PAS	OSF
Registered RWE trials, n (%)	102,471 (97.77%)	2275 (2.17%)	54 (0.05%)
RWE trials among registered RWE trials …
reporting Random Sampling, n (%)	27.562 (26.90%)	76 (3.34%)	6 (11.10%)
reporting Nonrandom Sampling, n (%)	70.787 (69.08%)	1 (<0.01%)	0 (0%)
not reporting on Sampling, n (%)	4.122 (4.02%)	2.198 (96.62%)	48 (88.89%)
RWE trials with Sample Correction Procedures among RWE trials reporting Nonrandom Sampling, n (%)	423 (0.60%)	0 (0.0%)	0 (0.0%)

Sources: clinicaltrials.gov, OSF‐RWE & EU‐PAS registries.