TABLE 1.
Host range of MLV(LCMV) pseudotypes
| Cell line (no. of expts) | Cell type | Mean vector titer relative to titer on SC-1 cells (range) |
|---|---|---|
| 293 (5) | Epithelial, human | 5.1 (1.2–16.7) |
| Te671 (5) | Fibroblast, Human | 16.5 (3.5–25) |
| K562 (5) | Myeloid progenitor, human | 0.26 (0.06–0.5) |
| TF-1 (4) | Myeloid progenitor, human | 0.14 (0.03–0.27) |
| HUH-7 (5) | Hepatoma, human | 0.08 (0.02–0.19) |
| nce-G112 (3) | Glioma, human | 3.44 (0.1–10) |
| CHO (4) | Epithelial, hamster | 0.7 (0.02–2.5) |
| Cf2Th (4) | Thymus stroma, dog | 15.3 (6–20) |
| Sc-1a | Fibroblast, mouse | 1 |
a
The titers on Sc-1 cells of the different virus stocks used here (non concentrated supernatants) ranged from 0.2 × 104 to 5 × 104 LTU per ml.