Schematic representation of the time course of the early biosynthetic events of the UUK virus spike proteins G1 and G2. The half times (T1/2) for disulfide bond formation, heterodimerization, acquisition of endo H resistance, and incorporation into virions are marked by arrows. The transient association of G1 and G2 with the ER chaperones BiP, calnexin, and calreticulin is indicated by bars.