Fig 4.

The putative glycolate/glyoxylate gene clusters in RHA1. GCL1 and GCL2 are clusters of paralogous genes encoding glycolate/glyoxylate catabolism (Table 2). (A) The GCL1 cluster (red) is part of the allantoin catabolic operon. (B) The broader genomic context of GCL1 includes genes involved in the mycothiol-dependent detoxification of formaldehyde (MDF). (C) The GCL2 cluster. (D) The genomic context of GCL2. Genes in green were upregulated on EG versus acetate. Genes in orange encode predicted transcription factors. The prefix “RHA1” of the gene IDs was omitted for simplicity. Genes in (B) and (D) are not drawn to scale.