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Scenario 2. Results from time concentration simulations using the PBK models for the four PFAS from birth to 75 years old (EFSA 2020 model) for exposure to (A) PFOA, (B) PFOS, (C) PFNA and (D) PFHxS all with an oral exposure of 0.628 ng/kg/day. This dose was selected as the oral exposure estimate from the EFSA 2020 TWI of 4.4 ng/kg. CA represents the total concentration of chemical in blood of the chemicals (ng/ml) (Y axis) and the time is expressed in years (x axis).
