Figure 5. PEDD-nelitolimod in combination with α-PD-1 improved the survival of tumor-bearing mice irrespective of the route of administration. Kaplan-Meier survival curve of liver metastases-bearing mice followed by intravascular PEDD nelitolimod with α-PD-1 administered either Sys or SQ. n denotes the number of mice in each group. Log-rank test was performed to determine the statistical differences among groups. n is mentioned in the individual graph. PEDD, pressure-enabled drug delivery; PD-1, programmed cell death-1; SQ, subcutaneous; Sys, systemic; Veh, vehicle.