USP36 expression is upregulated in CRC tissues and cells.A, USPs expression in tumor samples of patients with colorectal cancer from TCGA database. USP36 is marked. B, USP36 expression levels in colon adenocarcinoma (COAD) and rectum adenocarcinoma (READ) tumors versus normal samples in TCGA are shown in the histogram. C, USP36 expression in COAD and READ between normal and tumor tissues of different stages are presented in the histogram. D, Western blots of USP36 in CRC and control cell line NCM 460. CRC, colorectal cancer; TCGA, the Cancer Genome Atlas; USP36, ubiquitin-specific protease 36.