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. 2024 Jun 29;10(13):e33525. doi: 10.1016/j.heliyon.2024.e33525

Table 1.

All patients' characteristics. The table shows the characteristics of all patients participating in the study. The number of patients does not always add up to 100 % (n = 212) due to missing data for some attributes.

A studied cohort of patients Median age (years) [range] 60.92 [24–89]
%
n = 212
Tumor type
low-grade serous 9 4.2
high-grade serous 162 76.4
mucinous 11 5.2
clear cell 9 4.2
endometrioid 4 1.9
Brenner 1 0.5
borderline 1 0.5
adenocarcinoma 4 1.9
generalized disease 1 0.5
Grade
1 7 3.3
2 19 9.0
3 165 77.8
FIGO stagea
I 9 4.2
II 12 5.7
III 156 73.6
IV 15 7.1
Residual tumorb
yes 102 48.1
no 90 42.5
BRCA1/BRCA2 mutationc
yes 13 6.1
no 199 93.9
Therapy regimen
paclitaxel + platinum derivatives 162 76.4
platinum monotherapy 6 2.8
other regimend 10 4.7
none 1 0.5
Platinum-based therapy resistance
yes 60 28.3
no 106 50.0
Median platinum-free interval (PFI,months) [range]
platinum-resistant 5.31 (0–11.5)
platinum-sensitive 29.06 (12–97)
a

FIGO (International Federation of Gynecology and Obstetrics) staging system is used for ovarian, fallopian tube, and peritoneal cancer classification.

b

Residual tumor after surgery was defined by a surgeon as “yes” (macroscopic lesions <1 cm and peritoneal metastases >1 cm), or “no” [no macroscopic residuum (R)].

c

Breast cancer 1 and 2 (BRCA1/2) germline mutations are the most frequent causes of developing hereditary OvC.

d

Other regimen [paclitaxel + platinum derivate + cyclofosfamid, cisplatin + doxorubicin, oxaliplatin + capecitabine (known as XELOX), oxaliplatin + 5-fluorouracil + folinic acid (known as FOLFOX) administered in a regimen called modified FOLFOX6, or paclitaxel + carboplatin + bevacizumab].