Table 3.
PBL and tumor TL in patient subgroups. The table summarizes TL data measured in PBL and tumor tissues of patients diagnosed with OvC, along with various personal and clinicopathological characteristics.
| PBL |
Tumor tissue |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| n = 184 | % | Median TL (range) | P-value | n = 56 | % | Median TL (range) | P-value | ||
| Tumor type | |||||||||
| low-grade serous | 8 | 5 | 0.81 (0.71–1.25) | 0.68 (ANOVA) | 4 | 7.5 | 0.77 (0.69–0.99) | 0.94 (ANOVA) | |
| high-grade serous | 145 | 87 | 0.91 (0.45–1.47) | 37 | 70 | 0.68 (0.13–2.11) | |||
| mucinous | 6 | 4 | 0.91 (0.76–1.47) | 8 | 15 | 0.77 (0.33–1.47) | |||
| clear cell | 7 | 4 | 0.94 (0.80–1.29) | 4 | 7.5 | 0.95 (0.23–1.36) | |||
| Grade | |||||||||
| 1 | 5 | 3 | 0.82 (0.76–1.47) | 0.60 (ANOVA) | 4 | 7 | 0.72 (0.69–0.99) | 1 (ANOVA) | |
| 2 | 14 | 9 | 0.91 (0.63–1.23) | 8 | 14 | 0.87 (0.28–1.47) | |||
| 3 | 145 | 88 | 0.91 (0.46–1.47) | 44 | 79 | 0.75 (0.13–2.11) | |||
| FIGO stage | |||||||||
| I + II | 17 | 10 | 0.85 (0.63–1.47) | 0.44 (Mann-Whitney) | 7 | 13 | 0.69 (0.28–1.54) | 0.91 (Mann-Whitney) | |
| III + IV | 148 | 90 | 0.92 (0.46–1.47) | 48 | 87 | 0.79 (0.13–2.11) | |||
| Residual tumor | |||||||||
| yes | 89 | 53 | 0.90 (0.47–1.40) | 0.18 (t-test) | 31 | 55 | 0.81 (0.17–1.47) | 0.74 (t-test) | |
| no | 78 | 47 | 0.92 (0.46–1.47) | 25 | 45 | 0.69 (0.13–2.11) | |||
| Therapy resistance | |||||||||
| yes | 46 | 33 | 0.97 (0.48–1.47) | 0.037 (t-test) | 23 | 41 | 0.81 (0.17–1.54) | 0.45 (t-test) | |
| no | 93 | 67 | 0.89 (0.47–1.37) | 33 | 59 | 0.72 (0.13–2.11) | |||