Table 1.

Summary of health states included in each model

High risk group	Adverse events that are included in each model
Non-steroidal anti-inflammatory drug (NSAID) in older people without gastroprotection	Gastrointestinal discomfort, symptomatic ulcer, serious gastrointestinal event (eg, a bleed), death
NSAID with previous peptic ulcer with no gastroprotection	Gastrointestinal discomfort, symptomatic ulcer, serious gastrointestinal event (eg, a bleed), death
NSAID with oral anticoagulant	Gastrointestinal discomfort, symptomatic ulcer, serious gastrointestinal event (eg, a bleed), stroke, death
NSAID with heart failure	Minor heart failure exacerbation, major heart failure exacerbation requiring hospital admission, death
NSAID with chronic kidney disease	Acute kidney injury episode managed in primary care, acute kidney injury episode requiring hospital admission with or without renal replacement therapy, residual effect on kidney function, and progression of chronic kidney disease, death